Journal of Molecular Cell Biology Advance Access published online on September 30, 2009
Journal of Molecular Cell Biology, doi:10.1093/jmcb/mjp027
Embryonic vs. Adult Myogenesis: Challenging the Regeneration Recapitulates Development Paradigm
Department of Bioengineering, University of California, Berkeley, 174 Stanley Hall, Berkeley, CA 94720-1762, USA
* Correspondence to: Irina Conboy, E-mail: iconboy{at}berkeley.edu
| Abstract |
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A popular theory in the stem cell field is that regeneration recapitulates development, or that adult stem cells function similarly to embryonic ones. In a recent Nature article, Lepper et al. questioned this approach, highlighting the differences in requirements for Pax7 during myogenesis for embryonic, juvenile and adult muscle.