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Journal of Molecular Cell Biology Advance Access published online on September 23, 2009
Journal of Molecular Cell Biology, doi:10.1093/jmcb/mjp017
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© The Author (2009). Published by Oxford University Press on behalf of Journal of Molecular Cell Biology, IBCB, SIBS, CAS. All rights reserved.

The Emergence of Basophils as Antigen-Presenting Cells in Th2 Inflammatory Responses

Zamaneh Mikhak and Andrew D. Luster*

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02482, USA

* Correspondence to: Andrew D. Luster, E-mail: aluster{at}mgh.harvard.edu


  Abstract

Basophils gain prominence in Th2 inflammatory responses with the discovery that they function as antigen-presenting cells and are sufficient to drive Th2 cell differentiation.


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